翻訳と辞書 Words near each other ・ Tumor antigen ・ Tumor antigen vaccine ・ Tumor antigens recognized by T lymphocytes ・ Tumor Bank ・ Tumor board review ・ Tumor budding ・ Tumor Circus ・ Tumor hypoxia ・ Tumor initiation ・ Tumor lysis syndrome ・ Tumor M2-PK ・ Tumor marker ・ Tumor metabolome ・ Tumor microenvironment ・ Tumor necrosis factor alpha ・ Tumor necrosis factor receptor ・ Tumor necrosis factor receptor 1 ・ Tumor necrosis factor receptor 2 ・ Tumor necrosis factors ・ Tumor of the stomach ・ Tumor progression ・ Tumor promotion ・ Tumor reversion ・ Tumor suppressor gene ・ Tumor-associated calcium signal transducer ・ Tumor-associated glycoprotein ・ Tumor-associated glycoprotein 72 ・ Tumor-associated macrophage ・ Tumor-induced osteomalacia ・ Tumor-infiltrating lymphocytes Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Tumor necrosis factor receptor ： ウィキペディア英語版 Tumor necrosis factor receptor The tumor necrosis factor receptor superfamily (TNFRSF) is a group of cytokine receptors characterized by the ability to bind tumor necrosis factors (TNFs) via an extracellular cysteine-rich domain. With the exception of nerve growth factor (NGF), all TNFs are homologous to the archetypal TNF-alpha. In their active form, the majority of TNF receptors form trimeric complexes in the plasma membrame. Accordingly, most TNF receptors contain transmembrane domains (TMDs), although some can be cleaved into soluble forms (e.g. TNFR1), and some lack a TMD entirely (e.g. DcR3). In addition, most TNF receptors require specific adaptor protein such as TRADD, TRAF, RIP and FADD for downstream signalling. TNF receptors are primarily involved in apoptosis and inflammation, but they can also take part in other signal transduction pathways, such as proliferation, survival, and differentiation. TNF receptors are expressed in a wide variety of tissues in mammals, especially in leukocytes.〔 The term death receptor refers to those members of the TNF receptor superfamily that contain a death domain, such as TNFR1, Fas receptor, DR4 and DR5.〔 They were named after the fact that they seemed to play an important role in apoptosis (programmed cell death), although they are now known to play other roles as well. In the strict sense, the term TNF receptor is often used to refer to the archetypal members of the superfamily, namely TNFR1 and TNFR2, which recognize TNF-alpha. ==Members== There are 27 family members, numerically classified as TNFRSF#, where # denotes the member number, sometimes followed a letter.〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Tumor necrosis factor receptor」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.